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Targeting the ubiquitin system by fragment-based drug discovery

The ubiquitin system contains a wealth of potential drug targets for many diseases and conditions, including neurodegenerative, immune, metabolic and developmental diseases, as well as multiple cancers. Despite years of research, relatively few clinical inhibitors or specific chemical probes for pro...

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Detalles Bibliográficos
Autores principales: Kennedy, Cassandra, McPhie, Katherine, Rittinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580268/
https://www.ncbi.nlm.nih.gov/pubmed/36275626
http://dx.doi.org/10.3389/fmolb.2022.1019636