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CD8(+) T cell clonotypes from prior SARS-CoV-2 infection predominate during the cellular immune response to mRNA vaccination

Almost three years into the SARS-CoV-2 pandemic, hybrid immunity is highly prevalent worldwide and more protective than vaccination or prior infection alone. Given emerging resistance of variant strains to neutralizing antibodies (nAb), it is likely that T cells contribute to this protection. To und...

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Detalles Bibliográficos
Autores principales: Ford, Emily S., Mayer-Blackwell, Koshlan, Jing, Lichen, Sholukh, Anton M., St. Germain, Russell, Bossard, Emily L., Xie, Hong, Pulliam, Thomas H., Jani, Saumya, Selke, Stacy, Burrow, Carlissa J., McClurkan, Christopher L., Wald, Anna, Holbrook, Michael R., Eaton, Brett, Eudy, Elizabeth, Murphy, Michael, Postnikova, Elena, Robins, Harlan S., Elyanow, Rebecca, Gittelman, Rachel M., Ecsedi, Matyas, Wilcox, Elise, Chapuis, Aude G., Fiore-Gartland, Andrew, Koelle, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580387/
https://www.ncbi.nlm.nih.gov/pubmed/36263073
http://dx.doi.org/10.21203/rs.3.rs-2146712/v1