A senolysis-based theragnostic prodrug strategy towards chronic renal failure

Selective elimination of senescent cells (senolysis) has become a promising therapeutic strategy for the management of chronic renal failure (CRF), but the senolytic molecular pathways towards CRF therapy are limited. Here, we present for the first time a senescence-associated β-galactosidase (SA-β-...

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Detalles Bibliográficos
Autores principales: Song, Yihe, Li, Xinming, Shi, Donglei, Sun, Tianyue, Liu, Wenwen, Li, Xiaokang, Qiao, Sicong, Chen, Xin, Guo, Yuan, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580481/
https://www.ncbi.nlm.nih.gov/pubmed/36320912
http://dx.doi.org/10.1039/d2sc03525a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580481/
https://www.ncbi.nlm.nih.gov/pubmed/36320912
http://dx.doi.org/10.1039/d2sc03525a

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