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H-bond cooperativity: polarisation effects on secondary amides

Formation of a H-bond with an amide carbonyl oxygen atom increases the strength of subsequent H-bonds formed by the amide NH, due to polarisation of the bond. The magnitude of this effect has been quantified by measuring association constants for the formation of 1 : 1 complexes of 2-hydroxylbenzami...

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Detalles Bibliográficos
Autores principales: Soloviev, Daniil O., Hanna, Fergal E., Misuraca, Maria Cristina, Hunter, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580511/
https://www.ncbi.nlm.nih.gov/pubmed/36320903
http://dx.doi.org/10.1039/d2sc04271a