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Implications of the unfolded state in the folding energetics of heterogeneous-backbone protein mimetics

Sequence-encoded folding is the foundation of protein structure and is also possible in synthetic chains of artificial chemical composition. In natural proteins, the characteristics of the unfolded state are as important as those of the folded state in determining folding energetics. While much is k...

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Detalles Bibliográficos
Autores principales: Santhouse, Jacqueline R., Leung, Jeremy M. G., Chong, Lillian T., Horne, W. Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580521/
https://www.ncbi.nlm.nih.gov/pubmed/36320921
http://dx.doi.org/10.1039/d2sc04427g