Pathogenic and Commensal Gut Bacteria Harboring Glycerol/Diol Dehydratase Metabolize Glycerol and Produce DNA-Reactive Acrolein

[Image: see text] Bacteria harboring glycerol/diol dehydratase (GDH) encoded by the genes pduCDE metabolize glycerol and release acrolein during growth. Acrolein has antimicrobial activity, and exposure of human cells to acrolein gives rise to toxic and mutagenic responses. These biological response...

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Detalles Bibliográficos
Autores principales: Ramirez Garcia, Alejandro, Hurley, Katherine, Marastoni, Giovanni, Diard, Médéric, Hofer, Sophie, Greppi, Anna, Hardt, Wolf-Dietrich, Lacroix, Christophe, Sturla, Shana J., Schwab, Clarissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580524/
https://www.ncbi.nlm.nih.gov/pubmed/36116084
http://dx.doi.org/10.1021/acs.chemrestox.2c00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580524/
https://www.ncbi.nlm.nih.gov/pubmed/36116084
http://dx.doi.org/10.1021/acs.chemrestox.2c00137

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