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Pathogenic and Commensal Gut Bacteria Harboring Glycerol/Diol Dehydratase Metabolize Glycerol and Produce DNA-Reactive Acrolein
[Image: see text] Bacteria harboring glycerol/diol dehydratase (GDH) encoded by the genes pduCDE metabolize glycerol and release acrolein during growth. Acrolein has antimicrobial activity, and exposure of human cells to acrolein gives rise to toxic and mutagenic responses. These biological response...
Autores principales: | Ramirez Garcia, Alejandro, Hurley, Katherine, Marastoni, Giovanni, Diard, Médéric, Hofer, Sophie, Greppi, Anna, Hardt, Wolf-Dietrich, Lacroix, Christophe, Sturla, Shana J., Schwab, Clarissa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580524/ https://www.ncbi.nlm.nih.gov/pubmed/36116084 http://dx.doi.org/10.1021/acs.chemrestox.2c00137 |
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