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Losartan Attenuates Radiation-Induced Damage on Testes and Accelerates Tubular Regeneration

Male germ cells are particularly susceptible to radiation; infertility being a common consequence after radiotherapy as it impairs spermatogenesis. This study aimed to test whether treatment with losartan (LOS), a selective antagonist of angiotensin II receptor subtype 1 (AT1R), can prevent or atten...

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Detalles Bibliográficos
Autores principales: dos Santos, Lais L. Manção, Alves, Marco G., Chies, Agnaldo Bruno, Spadella, Maria Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580693/
https://www.ncbi.nlm.nih.gov/pubmed/36303628
http://dx.doi.org/10.3389/frph.2022.904804