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Irinotecan (CPT-11) Treatment Induces Mild Gonadotoxicity
BACKGROUND: Gonadal toxicity following chemotherapy is an important issue among the population of young cancer survivors. The inhibitor of DNA topoisomerase I, irinotecan (CPT-11), is widely used for several cancer types. However, little is known about the effect of irinotecan on the fertility of bo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580821/ https://www.ncbi.nlm.nih.gov/pubmed/36303648 http://dx.doi.org/10.3389/frph.2022.812053 |