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Assessing equivalent and inverse change in genes between diverse experiments

Background: It is important to identify when two exposures impact a molecular marker (e.g., a gene’s expression) in similar ways, for example, to learn that a new drug has a similar effect to an existing drug. Currently, statistically robust approaches for making comparisons of equivalence of effect...

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Detalles Bibliográficos
Autores principales: Neums, Lisa, Koestler, Devin C., Xia, Qing, Hu, Jinxiang, Patel, Shachi, Bell-Glenn, Shelby, Pei, Dong, Zhang, Bo, Boyd, Samuel, Chalise, Prabhakar, Thompson, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580844/
https://www.ncbi.nlm.nih.gov/pubmed/36304274
http://dx.doi.org/10.3389/fbinf.2022.893032