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DNA Methylation, Aging, and Cancer Risk: A Mini-Review

Accumulation of somatic mutations and genomic instability are hallmarks of both aging and cancer. Epigenetic alterations occur across cell types and tissues with advancing age. DNA methylation-based estimates of biologic age can predict important age-related outcomes, including risk of frailty and m...

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Detalles Bibliográficos
Autores principales: Chen, Larry, Ganz, Patricia A., Sehl, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580889/
https://www.ncbi.nlm.nih.gov/pubmed/36304336
http://dx.doi.org/10.3389/fbinf.2022.847629