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DNA Methylation, Aging, and Cancer Risk: A Mini-Review
Accumulation of somatic mutations and genomic instability are hallmarks of both aging and cancer. Epigenetic alterations occur across cell types and tissues with advancing age. DNA methylation-based estimates of biologic age can predict important age-related outcomes, including risk of frailty and m...
Autores principales: | Chen, Larry, Ganz, Patricia A., Sehl, Mary E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580889/ https://www.ncbi.nlm.nih.gov/pubmed/36304336 http://dx.doi.org/10.3389/fbinf.2022.847629 |
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