Cargando…

The Effect of Model Directionality on Cell-Type-Specific Differential DNA Methylation Analysis

Calling differential methylation at a cell-type level from tissue-level bulk data is a fundamental challenge in genomics that has recently received more attention. These studies most often aim at identifying statistical associations rather than causal effects. However, existing methods typically mak...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahmani, Elior, Jew, Brandon, Halperin, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580934/
https://www.ncbi.nlm.nih.gov/pubmed/36303752
http://dx.doi.org/10.3389/fbinf.2021.792605