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Protein structure prediction in the era of AI: Challenges and limitations when applying to in silico force spectroscopy
Mechanoactive proteins are essential for a myriad of physiological and pathological processes. Guided by the advances in single-molecule force spectroscopy (SMFS), we have reached a molecular-level understanding of how mechanoactive proteins sense and respond to mechanical forces. However, even SMFS...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580946/ https://www.ncbi.nlm.nih.gov/pubmed/36304287 http://dx.doi.org/10.3389/fbinf.2022.983306 |