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SETH predicts nuances of residue disorder from protein embeddings

Predictions for millions of protein three-dimensional structures are only a few clicks away since the release of AlphaFold2 results for UniProt. However, many proteins have so-called intrinsically disordered regions (IDRs) that do not adopt unique structures in isolation. These IDRs are associated w...

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Detalles Bibliográficos
Autores principales: Ilzhöfer, Dagmar, Heinzinger, Michael, Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580958/
https://www.ncbi.nlm.nih.gov/pubmed/36304335
http://dx.doi.org/10.3389/fbinf.2022.1019597