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Investigating the molecular mechanism of iguratimod act on SLE using network pharmacology and molecular docking analysis

Objective: Iguratimod (IGU) is a novel small disease-modifying compound widely used in Asia for the treatment of rheumatic diseases. IGU is a methane sulfonanilide. We applied network pharmacology to investigate the pharmacological mechanisms of IGU act on SLE. Methods: We used PharmMapper, UniProt,...

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Detalles Bibliográficos
Autores principales: Zeng, Huiqiong, Chen, Shuai, Lu, Xiaoping, Yan, Zhenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580962/
https://www.ncbi.nlm.nih.gov/pubmed/36304300
http://dx.doi.org/10.3389/fbinf.2022.932114