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Protein Complex Organization Imposes Constraints on Proteome Dysregulation in Cancer

Protein assembly is a highly dynamic process and proteins can interact in different ways and stoichiometries within a complex. The importance of maintaining protein stoichiometry for complex function and avoiding aggregation of orphan subunits has been demonstrated. However, how exactly the organiza...

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Detalles Bibliográficos
Autores principales: Senger, Gökçe, Schaefer, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580999/
https://www.ncbi.nlm.nih.gov/pubmed/36303728
http://dx.doi.org/10.3389/fbinf.2021.723482