Data Driven Cell Cycle Model to Quantify the Efficacy of Cancer Therapeutics Targeting Specific Cell-Cycle Phases From Flow Cytometry Results

Many chemotherapeutic drugs target cell processes in specific cell cycle phases. Determining the specific phases targeted is key to understanding drug mechanism of action and efficacy against specific cancer types. Flow cytometry experiments, combined with cell cycle phase and division round specifi...

Descripción completa

Detalles Bibliográficos
Autores principales: James, David W., Filby, Andrew, Brown, M. Rowan, Summers, Huw D., Francis, Lewis W., Rees, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581040/
https://www.ncbi.nlm.nih.gov/pubmed/36303763
http://dx.doi.org/10.3389/fbinf.2021.662210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581040/
https://www.ncbi.nlm.nih.gov/pubmed/36303763
http://dx.doi.org/10.3389/fbinf.2021.662210

Ejemplares similares