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A Tool for Segmentation of Secondary Structures in 3D Cryo-EM Density Map Components Using Deep Convolutional Neural Networks

Although cryo-electron microscopy (cryo-EM) has been successfully used to derive atomic structures for many proteins, it is still challenging to derive atomic structures when the resolution of cryo-EM density maps is in the medium resolution range, such as 5–10 Å. Detection of protein secondary stru...

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Detalles Bibliográficos
Autores principales: Mu, Yongcheng, Sazzed, Salim, Alshammari, Maytha, Sun, Jiangwen, He, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581063/
https://www.ncbi.nlm.nih.gov/pubmed/36303800
http://dx.doi.org/10.3389/fbinf.2021.710119