Smooth muscle Acid-sensing ion channel 1a as a therapeutic target to reverse hypoxic pulmonary hypertension

Acid-sensing ion channel 1a (ASIC1a) is a voltage-independent, non-selective cation channel that conducts both Na(+) and Ca(2+). Activation of ASIC1a elicits plasma membrane depolarization and stimulates intracellular Ca(2+)-dependent signaling pathways in multiple cell types, including vascular smo...

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Detalles Bibliográficos
Autores principales: Garcia, Selina M., Yellowhair, Tracy R., Detweiler, Neil D., Ahmadian, Rosstin, Herbert, Lindsay M., Gonzalez Bosc, Laura V., Resta, Thomas C., Jernigan, Nikki L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581175/
https://www.ncbi.nlm.nih.gov/pubmed/36275633
http://dx.doi.org/10.3389/fmolb.2022.989809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581175/
https://www.ncbi.nlm.nih.gov/pubmed/36275633
http://dx.doi.org/10.3389/fmolb.2022.989809

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