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Smooth muscle Acid-sensing ion channel 1a as a therapeutic target to reverse hypoxic pulmonary hypertension
Acid-sensing ion channel 1a (ASIC1a) is a voltage-independent, non-selective cation channel that conducts both Na(+) and Ca(2+). Activation of ASIC1a elicits plasma membrane depolarization and stimulates intracellular Ca(2+)-dependent signaling pathways in multiple cell types, including vascular smo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581175/ https://www.ncbi.nlm.nih.gov/pubmed/36275633 http://dx.doi.org/10.3389/fmolb.2022.989809 |