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Development and validation of a sensitive LC-MS/MS method for determination of intracellular concentration of fluconazole in Candida albicans
Systemic candidiasis is the fourth leading cause of healthcare-associated infections worldwide. The combination therapy based on existing antifungal agents is well-established to overcome drug resistance and restore antifungal efficacy against drug-resistant strains. In this study, a simple and sens...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581211/ https://www.ncbi.nlm.nih.gov/pubmed/36274702 http://dx.doi.org/10.3389/fmicb.2022.1007576 |