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Development and validation of a sensitive LC-MS/MS method for determination of intracellular concentration of fluconazole in Candida albicans

Systemic candidiasis is the fourth leading cause of healthcare-associated infections worldwide. The combination therapy based on existing antifungal agents is well-established to overcome drug resistance and restore antifungal efficacy against drug-resistant strains. In this study, a simple and sens...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaofei, Wang, Xiaojuan, Cai, Tongkai, Qin, Yulin, Li, Ling, Jiang, Yuanying, Han, Bing, Cao, Yongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581211/ https://www.ncbi.nlm.nih.gov/pubmed/36274702 http://dx.doi.org/10.3389/fmicb.2022.1007576

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