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Tsc2 shapes olfactory bulb granule cell molecular and morphological characteristics

Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations that inactivate TSC1 or TSC2. Hamartin and tuberin are encoded by TSC1 and TSC2 which form a GTPase activating protein heteromer that inhibits the Rheb GTPase from activating a growth promoting protein kinase calle...

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Detalles Bibliográficos
Autores principales: Riley, Victoria A., Holmberg, Jennie C., Sokolov, Aidan M., Feliciano, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581303/
https://www.ncbi.nlm.nih.gov/pubmed/36277492
http://dx.doi.org/10.3389/fnmol.2022.970357