Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7

BACKGROUND: Previous studies implicated matrix metalloproteinases (MMPs), such as MMP-7, in inflammatory bowel diseases (IBD) by showing increased activity during inflammation of the gut. However, the pathophysiological roles of MMP-7 have not been clearly elucidated. METHODS: The expression of MMP-...

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Detalles Bibliográficos
Autores principales: Xiao, Ying, Lian, Haifeng, Zhong, Xiaoying S., Krishnachaitanya, Srikruthi S., Cong, Yingzi, Dashwood, Roderick H., Savidge, Tor C., Powell, Don W., Liu, Xiaowei, Li, Qingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581388/
https://www.ncbi.nlm.nih.gov/pubmed/36275703
http://dx.doi.org/10.3389/fimmu.2022.1020902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581388/
https://www.ncbi.nlm.nih.gov/pubmed/36275703
http://dx.doi.org/10.3389/fimmu.2022.1020902

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