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Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7
BACKGROUND: Previous studies implicated matrix metalloproteinases (MMPs), such as MMP-7, in inflammatory bowel diseases (IBD) by showing increased activity during inflammation of the gut. However, the pathophysiological roles of MMP-7 have not been clearly elucidated. METHODS: The expression of MMP-...
Autores principales: | Xiao, Ying, Lian, Haifeng, Zhong, Xiaoying S., Krishnachaitanya, Srikruthi S., Cong, Yingzi, Dashwood, Roderick H., Savidge, Tor C., Powell, Don W., Liu, Xiaowei, Li, Qingjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581388/ https://www.ncbi.nlm.nih.gov/pubmed/36275703 http://dx.doi.org/10.3389/fimmu.2022.1020902 |
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