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LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model

Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. However, the pathogenic mechanisms of OT have not been well elucidated. Here, we used C57BL/6 (B6) mice to establish OT by peroral infection with 20 cysts of the TgCtWh6 strain, and severe ocular damage was observed by...

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Detalles Bibliográficos
Autores principales: Gao, Nannan, Wang, Chong, Yu, Yiran, Xie, Linding, Xing, Yien, Zhang, Yuan, Wang, Yanling, Wu, Jianjun, Cai, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581422/
https://www.ncbi.nlm.nih.gov/pubmed/36206304
http://dx.doi.org/10.1371/journal.pntd.0010848