Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed that, in each resistant...

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Detalles Bibliográficos
Autores principales: Alpizar-Sosa, Edubiel A., Ithnin, Nur Raihana Binti, Wei, Wenbin, Pountain, Andrew W., Weidt, Stefan K., Donachie, Anne M., Ritchie, Ryan, Dickie, Emily A., Burchmore, Richard J. S., Denny, Paul W., Barrett, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581426/
https://www.ncbi.nlm.nih.gov/pubmed/36170238
http://dx.doi.org/10.1371/journal.pntd.0010779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581426/
https://www.ncbi.nlm.nih.gov/pubmed/36170238
http://dx.doi.org/10.1371/journal.pntd.0010779

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