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Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response
Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed that, in each resistant...
Autores principales: | Alpizar-Sosa, Edubiel A., Ithnin, Nur Raihana Binti, Wei, Wenbin, Pountain, Andrew W., Weidt, Stefan K., Donachie, Anne M., Ritchie, Ryan, Dickie, Emily A., Burchmore, Richard J. S., Denny, Paul W., Barrett, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581426/ https://www.ncbi.nlm.nih.gov/pubmed/36170238 http://dx.doi.org/10.1371/journal.pntd.0010779 |
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