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Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward

Dopamine signaling from the ventral tegmental area (VTA) plays critical roles in reward-related behaviors, but less is known about the functions of neighboring VTA GABAergic neurons. We show here that a primary target of VTA GABA projection neurons is the ventral pallidum (VP). Activity of VTA-to-VP...

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Detalles Bibliográficos
Autores principales: Zhou, Wen-Liang, Kim, Kristen, Ali, Farhan, Pittenger, Steven T., Calarco, Cali A., Mineur, Yann S., Ramakrishnan, Charu, Deisseroth, Karl, Kwan, Alex C., Picciotto, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581470/
https://www.ncbi.nlm.nih.gov/pubmed/36260661
http://dx.doi.org/10.1126/sciadv.abm5217