Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice

Aging is associated with an increased risk of frailty, disability, and mortality. Strategies to delay the degenerative changes associated with aging and frailty are particularly interesting. We treated old animals with small extracellular vesicles (sEVs) derived from adipose mesenchymal stem cells (...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanz-Ros, Jorge, Romero-García, Nekane, Mas-Bargues, Cristina, Monleón, Daniel, Gordevicius, Juozas, Brooke, Robert T., Dromant, Mar, Díaz, Ana, Derevyanko, Aksinya, Guío-Carrión, Ana, Román-Domínguez, Aurora, Inglés, Marta, Blasco, María A., Horvath, Steve, Viña, Jose, Borrás, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581480/
https://www.ncbi.nlm.nih.gov/pubmed/36260670
http://dx.doi.org/10.1126/sciadv.abq2226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581480/
https://www.ncbi.nlm.nih.gov/pubmed/36260670
http://dx.doi.org/10.1126/sciadv.abq2226

Ejemplares similares