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Perinatal Morphine Exposure Leads to Sex-Dependent Executive Function Deficits and Microglial Changes in Mice

Children exposed prenatally to opioids are at an increased risk for behavioral problems and executive function deficits. The prefrontal cortex (PFC) and amygdala (AMG) regulate executive function and social behavior and are sensitive to opioids prenatally. Opioids can bind to toll-like receptor 4 (T...

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Detalles Bibliográficos
Autores principales: Smith, Brittany L., Guzman, Tess A., Brendle, Alexander H., Laaker, Collin J., Ford, Alexis, Hiltz, Adam R., Zhao, Junfang, Setchell, Kenneth D. R., Reyes, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581576/
https://www.ncbi.nlm.nih.gov/pubmed/36216505
http://dx.doi.org/10.1523/ENEURO.0238-22.2022