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AP2 Regulates Thickveins Trafficking to Attenuate NMJ Growth Signaling in Drosophila

Compromised endocytosis in neurons leads to synapse overgrowth and altered organization of synaptic proteins. However, the molecular players and the signaling pathways which regulate the process remain poorly understood. Here, we show that σ2-adaptin, one of the subunits of the AP2-complex, genetica...

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Detalles Bibliográficos
Autores principales: Choudhury, Saumitra Dey, Dwivedi, Manish Kumar, Pippadpally, Srikanth, Patnaik, Abhinandan, Mishra, Shirish, Padinjat, Raghu, Kumar, Vimlesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581581/
https://www.ncbi.nlm.nih.gov/pubmed/36180220
http://dx.doi.org/10.1523/ENEURO.0044-22.2022