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Identification of a 5-Hydroxymethylation Signature in Circulating Cell-Free DNA for the Noninvasive Detection of Colorectal Cancer

BACKGROUND: As a crucial epigenetic modification, DNA 5-hydroxymethylcytosine (5-hmC) plays a key role during colorectal cancer (CRC) carcinogenesis. Nevertheless, the levels of 5-hmC-related genes in the circulating DNA of CRC remain largely unknown. METHODS AND RESULTS: The GSE81314 dataset from t...

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Detalles Bibliográficos
Autores principales: Liu, Hongwei, Tang, Tao, Zhang, Huixian, Ting, Weiren, Zhou, Peng, Luo, Ying, Qi, Huaxing, Liu, Yanmei, Liu, Yongxin, Zhou, Meifang, Yin, Weiguo, Lin, Jinduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581595/
https://www.ncbi.nlm.nih.gov/pubmed/36276281
http://dx.doi.org/10.1155/2022/3798741