YTHDF2 Regulates Macrophage Polarization through NF-κB and MAPK Signaling Pathway Inhibition or p53 Degradation

Macrophages are heterogeneous cells that can be polarized into M1 or M2 phenotype. m(6)A “reader” YTH domain family protein 2 (YTHDF2) has been the m(6)A binding protein with the highest activity, which can recognize and disturb m(6)A-containing mRNA in processing bodies to reduce mRNA stability. YT...

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Detalles Bibliográficos
Autores principales: Cai, Luhui, Li, Di, Feng, Zhihui, Gu, Xiaofei, Xu, Qiong, Li, Qimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581620/
https://www.ncbi.nlm.nih.gov/pubmed/36277978
http://dx.doi.org/10.1155/2022/3153362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581620/
https://www.ncbi.nlm.nih.gov/pubmed/36277978
http://dx.doi.org/10.1155/2022/3153362

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