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YTHDF2 Regulates Macrophage Polarization through NF-κB and MAPK Signaling Pathway Inhibition or p53 Degradation

Macrophages are heterogeneous cells that can be polarized into M1 or M2 phenotype. m(6)A “reader” YTH domain family protein 2 (YTHDF2) has been the m(6)A binding protein with the highest activity, which can recognize and disturb m(6)A-containing mRNA in processing bodies to reduce mRNA stability. YT...

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Detalles Bibliográficos
Autores principales:	Cai, Luhui, Li, Di, Feng, Zhihui, Gu, Xiaofei, Xu, Qiong, Li, Qimeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581620/ https://www.ncbi.nlm.nih.gov/pubmed/36277978 http://dx.doi.org/10.1155/2022/3153362

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