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Homologous peptides derived from influenza A, B and C viruses induce variable CD8 (+) T cell responses with cross‐reactive potential

OBJECTIVE: Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally, infecting humans and causing widespread morbidity and mortality. Here, we investigate the T cell response towards an immunodominant IAV epitope, NP(265‐273,) and its IBV and ICV homologues, presented by HLA‐...

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Detalles Bibliográficos
Autores principales: Nguyen, Andrea T, Lau, Hiu Ming Peter, Sloane, Hannah, Jayasinghe, Dhilshan, Mifsud, Nicole A, Chatzileontiadou, Demetra SM, Grant, Emma J, Szeto, Christopher, Gras, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581725/
https://www.ncbi.nlm.nih.gov/pubmed/36275878
http://dx.doi.org/10.1002/cti2.1422