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Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer

The complex immunosuppressive tumour microenvironment (TME) and lack of tumour-specific targets hinder the application of chimeric antigen receptor (CAR) T cells in the treatment of solid tumours. Combining local treatment with CAR T cell immunotherapy may regulate the TME and enhance the killing po...

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Detalles Bibliográficos
Autores principales: Cao, Bihui, Liu, Manting, Wang, Lu, Zhu, Kangshun, Cai, Mingyue, Chen, Xiaopei, Feng, Yunfei, Yang, Shuo, Fu, Shengyu, Zhi, Cheng, Ye, Xiaodie, Zhang, Jian, Zhang, Zhiru, Yang, Xin, Zhao, Ming, Wu, Qingde, Xu, Linfeng, Yang, Lili, Lian, Hui, Zhao, Qi, Zhang, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581911/
https://www.ncbi.nlm.nih.gov/pubmed/36261437
http://dx.doi.org/10.1038/s41467-022-33968-5