HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids

Human organoids could facilitate research of complex and currently incurable neuropathologies, such as age-related macular degeneration (AMD) which causes blindness. Here, we establish a human retinal organoid system reproducing several parameters of the human retina, including some within the macul...

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Detalles Bibliográficos
Autores principales: Völkner, Manuela, Wagner, Felix, Steinheuer, Lisa Maria, Carido, Madalena, Kurth, Thomas, Yazbeck, Ali, Schor, Jana, Wieneke, Stephanie, Ebner, Lynn J. A., Del Toro Runzer, Claudia, Taborsky, David, Zoschke, Katja, Vogt, Marlen, Canzler, Sebastian, Hermann, Andreas, Khattak, Shahryar, Hackermüller, Jörg, Karl, Mike O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581928/
https://www.ncbi.nlm.nih.gov/pubmed/36261438
http://dx.doi.org/10.1038/s41467-022-33848-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581928/
https://www.ncbi.nlm.nih.gov/pubmed/36261438
http://dx.doi.org/10.1038/s41467-022-33848-y

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