Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor

The zinc-dependent metalloprotease meprin α is predominantly expressed in the brush border membrane of proximal tubules in the kidney and enterocytes in the small intestine and colon. In normal tissue homeostasis meprin α performs key roles in inflammation, immunity, and extracellular matrix remodel...

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Detalles Bibliográficos
Autores principales: Bayly-Jones, Charles, Lupton, Christopher J., Fritz, Claudia, Venugopal, Hariprasad, Ramsbeck, Daniel, Wermann, Michael, Jäger, Christian, de Marco, Alex, Schilling, Stephan, Schlenzig, Dagmar, Whisstock, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581967/
https://www.ncbi.nlm.nih.gov/pubmed/36261433
http://dx.doi.org/10.1038/s41467-022-33893-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581967/
https://www.ncbi.nlm.nih.gov/pubmed/36261433
http://dx.doi.org/10.1038/s41467-022-33893-7

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