CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase

Pyruvate carboxylase (PC) is a tetrameric enzyme that contains two active sites per subunit that catalyze two consecutive reactions. A mobile domain with an attached prosthetic biotin links both reactions, an initial biotin carboxylation and the subsequent carboxyl transfer to pyruvate substrate to...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Alonso, Jorge Pedro, Lázaro, Melisa, Gil-Cartón, David, Choi, Philip H., Dodu, Alexandra, Tong, Liang, Valle, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581989/
https://www.ncbi.nlm.nih.gov/pubmed/36261450
http://dx.doi.org/10.1038/s41467-022-33987-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581989/
https://www.ncbi.nlm.nih.gov/pubmed/36261450
http://dx.doi.org/10.1038/s41467-022-33987-2

Ejemplares similares