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Characterizing the metabolic effects of the selective inhibition of gut microbial β-glucuronidases in mice
The hydrolysis of xenobiotic glucuronides by gut bacterial glucuronidases reactivates previously detoxified compounds resulting in severe gut toxicity for the host. Selective bacterial β-glucuronidase inhibitors can mitigate this toxicity but their impact on wider host metabolic processes has not be...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9581996/ https://www.ncbi.nlm.nih.gov/pubmed/36261446 http://dx.doi.org/10.1038/s41598-022-21518-4 |