The unfolded protein response reverses the effects of glucose on lifespan in chemically-sterilized C. elegans

Metabolic diseases often share common traits, including accumulation of unfolded proteins in the endoplasmic reticulum (ER). Upon ER stress, the unfolded protein response (UPR) is activated to limit cellular damage which weakens with age. Here, we show that Caenorhabditis elegans fed a bacterial die...

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Detalles Bibliográficos
Autores principales: Beaudoin-Chabot, Caroline, Wang, Lei, Celik, Cenk, Abdul Khalid, Aishah Tul-Firdaus, Thalappilly, Subhash, Xu, Shiyi, Koh, Jhee Hong, Lim, Venus Wen Xuan, Low, Ann Don, Thibault, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582010/
https://www.ncbi.nlm.nih.gov/pubmed/36261415
http://dx.doi.org/10.1038/s41467-022-33630-0

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