ACVR1-activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans

Altered bone morphogenetic protein (BMP) signaling is associated with many musculoskeletal diseases. However, it remains unknown whether BMP dysfunction has direct contribution to debilitating pain reported in many of these disorders. Here, we identified a novel neuropathic pain phenotype in patient...

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Detalles Bibliográficos
Autores principales: Yu, Xiaobing, Ton, Amy N., Niu, Zejun, Morales, Blanca M., Chen, Jiadong, Braz, Joao, Lai, Michael H., Barruet, Emilie, Liu, Hongju, Cheung, Kin, Ali, Syed, Chan, Tea, Bigay, Katherine, Ho, Jennifer, Nikolli, Ina, Hansberry, Steven, Wentworth, Kelly, Kriegstein, Arnold, Basbaum, Allan, Hsiao, Edward C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582048/
https://www.ncbi.nlm.nih.gov/pubmed/35442931
http://dx.doi.org/10.1097/j.pain.0000000000002656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582048/
https://www.ncbi.nlm.nih.gov/pubmed/35442931
http://dx.doi.org/10.1097/j.pain.0000000000002656

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