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Epidemiological evidence for associations between variants in CHRNA genes and risk of lung cancer and chronic obstructive pulmonary disease

BACKGROUND: Genetic studies have previously reported that single-nucleotide polymorphisms (SNPs) in CHRNA genes (such as CHRNA3, CHRNA4, CHRNA5, or CHRNA3-CHRNA5-CHRNB4 clusters) are linked to the risk of neoplastic and non-neoplastic diseases. However, these conclusions were controversial and no sy...

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Detalles Bibliográficos
Autores principales: Yang, Lei, Yang, Zelin, Zuo, Chunjian, Lv, Xiaolong, Liu, Tianyu, Jia, Chenhao, Chen, Huanwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582127/
https://www.ncbi.nlm.nih.gov/pubmed/36276121
http://dx.doi.org/10.3389/fonc.2022.1001864