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Sec61 complex/translocon: The role of an atypical ER Ca(2+)-leak channel in health and disease
The heterotrimeric Sec61 protein complex forms the functional core of the so-called translocon that forms an aqueous channel in the endoplasmic reticulum (ER). The primary role of the Sec61 complex is to allow protein import in the ER during translation. Surprisingly, a completely different function...
Autores principales: | Parys, Jan B., Van Coppenolle, Fabien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582130/ https://www.ncbi.nlm.nih.gov/pubmed/36277220 http://dx.doi.org/10.3389/fphys.2022.991149 |
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