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Molecular and clinicopathological characteristics of ERBB2 gene fusions in 32,131 Chinese patients with solid tumors

ERBB2 amplification is one of the most important and mature targets for HER2-targeted drug therapy. Somatic mutations of ERBB2 in the tyrosine kinase domain have been studied extensively, and play a role in response to anti-HER2 therapy among different cancer types. However, ERBB2 fusion has not bee...

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Detalles Bibliográficos
Autores principales: Guan, Yin, Wang, Yutong, Li, Hongxia, Meng, Jing, You, Xia, Zhu, Xiaofeng, Zhang, Qin, Sun, Tingting, Qi, Chuang, An, Guangyu, Fan, Ying, Xu, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582139/
https://www.ncbi.nlm.nih.gov/pubmed/36276102
http://dx.doi.org/10.3389/fonc.2022.986674