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Association of KCNJ6 rs2070995 and methadone response for pain management in advanced cancer at end-of-life

Opioids are the therapeutic agents of choice to manage moderate to severe pain in patients with advanced cancer, however the unpredictable inter-individual response to opioid therapy remains a challenge for clinicians. While studies are few, the KCNJ6 gene is a promising target for investigating gen...

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Detalles Bibliográficos
Autores principales: Ozberk, Deniz, Haywood, Alison, Sutherland, Heidi G., Yu, Chieh, Albury, Cassie L., Zunk, Mathew, George, Rani, Good, Phillip, Griffiths, Lyn R., Hardy, Janet, Haupt, Larisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582209/
https://www.ncbi.nlm.nih.gov/pubmed/36261449
http://dx.doi.org/10.1038/s41598-022-21180-w