METTL3-IGF2BP3-axis mediates the proliferation and migration of pancreatic cancer by regulating spermine synthase m6A modification

Spermine synthase (SMS) is an enzyme participating in polyamine synthesis; however, its function and role in pancreatic cancer remains elusive. Here we report that SMS is upregulated in pancreatic cancer and predicts a worse overall survival and significantly promotes the proliferation and migration...

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Detalles Bibliográficos
Autores principales: Guo, Zhenyun, Zhang, Xiang, Lin, Chengjie, Huang, Yue, Zhong, Yun, Guo, Hailing, Zheng, Zhou, Weng, Shangeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582246/
https://www.ncbi.nlm.nih.gov/pubmed/36276112
http://dx.doi.org/10.3389/fonc.2022.962204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582246/
https://www.ncbi.nlm.nih.gov/pubmed/36276112
http://dx.doi.org/10.3389/fonc.2022.962204

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