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UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy derived from early T cell progenitors. Since relapsed T-ALL is associated with a poor prognosis improving initial treatment of patients is essential to avoid resistant selection of T-ALL. During initiation, developme...

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Detalles Bibliográficos
Autores principales: Sancerni, Tiphaine, Renoult, Ophélie, Luby, Angèle, Caradeuc, Cédric, Lenoir, Véronique, Croyal, Mikael, Ransy, Céline, Aguilar, Esther, Postic, Catherine, Bertho, Gildas, Dentin, Renaud, Prip-Buus, Carina, Pecqueur, Claire, Alves-Guerra, Marie-Clotilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582289/
https://www.ncbi.nlm.nih.gov/pubmed/36275699
http://dx.doi.org/10.3389/fimmu.2022.960226